Host: Rabbit
Target Protein: SLC20A2
IR: Immunogen Range:51-150/652
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6575
Swiss Prot: Q08357
Source:
KLH conjugated synthetic peptide derived from human SLC20A2/PIT2:51-150/652
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The SLC20 family transport proteins were originally identified as retroviral receptors Glvr-1 and Ram-1, but are now designated sodium-dependent phosphate transporters 1 and 2 (PiT1 and PiT2). The PiT proteins function as sodium-phosphate cotransporters and are widely expressed, with high expression in bone, kidney and intestine. Both PiT1 and PiT2 are expressed on polarized epithelial cell membranes where they play a role in cellular phosphate homeostasis. PiT2 is a human receptor for amphotropic murine leukemia virus (A-MuLV). A-MuLV infects a variety of mammalian cell lines, including humans, making it a useful tool in gene transfer technology and as a vector for gene therapy. Retroviral vector systems are used in gene therapy that are designed to infect cells expressing PiT1 or PiT2.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Horse)
For research use only. Not intended for diagnostic or therapeutic use.