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Host: Rabbit
Target Protein: HIF-1 Alpha
IR: Immunogen Range:451-550/826
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3091
Swiss Prot: Q16665
Source: KLH conjugated synthetic peptide derived from human HIF-1 Alpha:451-550/826
Purification: affinity purified by Protein A
Storage: Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1μg/Test,ICC/IF=1:100,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
For research use only. Not intended for diagnostic or therapeutic use.
