Host: Rabbit
Target Protein: Phospho-GRB10 (Tyr67)
IR: Immunogen Range:SL(p-Y)SA
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 2887
Swiss Prot: Q13322
Source: KLH conjugated Synthesised phosphopeptide derived from human GRB10 around the phosphorylation site of Tyr67:SL(p-Y)SA
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse (predicted: Rabbit,Horse)
For research use only. Not intended for diagnostic or therapeutic use.