Host: Rabbit
Target Protein: Amylin
IR: Immunogen Range:1-37/89
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3375
Swiss Prot: P10997
Source: KLH conjugated synthetic peptide derived from human Amylin:1-37/89
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.