bs-6139R [Primary Antibody]
Rabbit  Anti-KDM5B  Polyclonal Antibody
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Host: Rabbit

Target Protein: KDM5B

IR: Immunogen Range:65-165/1544

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10765

Swiss Prot: Q9UGL1

Source: KLH conjugated synthetic peptide derived from human KDM5B/PLU1/Jarid1B:65-165/1544 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.

Size: 50ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=3ug/test, ELISA=1:5000-10000

Cross Reactive Species: Human,Rat (predicted: Mouse,Chicken,Dog,Pig,Cow,Horse,GuineaPig)

For research use only. Not intended for diagnostic or therapeutic use.

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