Host: Rabbit

Target Protein: SFRP1

IR: Immunogen Range:201-314/314

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6422

Swiss Prot: Q8N474

Source: KLH conjugated synthetic peptide derived from human SFRP1:201-314/314 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]