Host: Rabbit
Target Protein: GNAQ
IR: Immunogen Range:51-150/359
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 2776
Swiss Prot: P50148
Source: KLH conjugated synthetic peptide derived from human GNAQ:51-150/359
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Pig,Cow,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.