Host: Rabbit
Target Protein: SPHK1, Alexa Fluor 750 conjugated
IR: Immunogen Range:1-100/384
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8877
Swiss Prot: Q9NYA1
Source: KLH conjugated synthetic peptide derived from human SPHK1:1-100/384
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Size: 100ul
Concentration: 1mg/ml
Applications:
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.