Host: Rabbit
Target Protein: DUSP1
IR: Immunogen Range:100-160/367
Clonality:
Isotype: IgG
Entrez Gene: 1843
Swiss Prot: P28562
Source: KLH conjugated synthetic peptide derived from human DUSP1:100-160/367
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:100-500, Flow-Cyt=1:50-100
Cross Reactive Species: (predicted: Human,Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.