Host: Mouse

Target Protein: MUC16

IR: Immunogen Range:12660-12923/14507

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 94025

Swiss Prot: Q8WXI7

Source: Recombinant human MUC16 Protein:12660-12923/14507 

Purification: affinity purified by Protein A

Storage:  Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.