Host: Mouse

Target Protein: CRP

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 1401

Swiss Prot: P02741

Source: Human CRP protein: 

Purification: affinity purified by Protein A

Storage: 0.01M PBS(pH7.4)  Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated in innate immunity. CRP binds to ligands containing phosphocholine, SAP binds to amyloid fibrils, DNA, chromatin, fibronectin, C4-binding proteins and glycosaminoglycans. "Long" pentraxins have N-terminal extensions to the common pentraxin domain; one group, the neuronal pentraxins, may be involved in synapse formation and remodeling, and they may also be able to form heteromultimers.