Host: Rabbit
Target Protein: TNFRSF12A/CD266
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 51330
Swiss Prot: Q9NP84
Source: KLH conjugated synthetic peptide derived from human TWEAKR:
Purification: affinity purified by Protein A
Storage: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.
Function : Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:300-5000, IHC-P=1:100-500
Cross Reactive Species: (predicted: Human,Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.