Host: Rabbit
Target Protein: Ki67
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 4288
Swiss Prot: P46013
Source: KLH conjugated synthetic peptide derived from human Ki67:
Purification: affinity purified by Protein A
Storage: PBS, Glycerol, BSA Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, ICC=1:50-100, IF=1:50-100
Cross Reactive Species: Rat,Mouse (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.