Host: Rabbit

Target Protein: ARHGAP24

IR: Immunogen Range:1-202/748

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 83478

Swiss Prot: Q8N264

Source: Recombinant human ARHGAP24 protein :1-202/748 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.  Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]