Host: Rabbit
Target Protein: Bak / Biotin
IR: Immunogen Range:71-171/211
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 578
Swiss Prot: O08734
Source: KLH conjugated synthetic peptide derived from human Bak:71-171/211
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications:
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.