Host: Rabbit

Target Protein: Histone H1.4 (Acetyl K53)

IR: Immunogen Range:AS(Ac-K)ER

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3008

Swiss Prot: P10412

Source: KLH conjugated Synthesised acetylpeptide derived from human Histone H1b around the acetylation site of Lys53:AS(Ac-K)ER 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.