Host: Rabbit
Target Protein: WIPF2
IR: Immunogen Range:31-130/440
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 147179
Swiss Prot: Q8TF74
Source: KLH conjugated synthetic peptide derived from human WIPF2:31-130/440
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: WIRE, also known as WIPF2 (WAS/WASL interacting protein family, member 2) or WICH, is a 440 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one WH2 domain. Expressed ubiquitously with highest expression in colon, brain, lung and stomach, WIRE functions as an N-WASP-interacting protein that plays an important role in the organization and mobilization of the Actin cytoskeleton. Additionally, WIRE is involved in the formation of cell surface protrusions and may also provide a link between the cytoskeletal machinery and PDGF-B receptors. Multiple alternatively spliced isoforms of WIRE exist and are encoded by a gene that maps to human chromosome 17.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:50-200, ELISA=1:5000-10000
Cross Reactive Species: Human,Rat (predicted: Mouse,Dog,Pig)
For research use only. Not intended for diagnostic or therapeutic use.