Host: Rabbit
Target Protein: IGF2R/M6PR
IR: Immunogen Range:2201-2400/2491
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3482
Swiss Prot: P11717
Source: KLH conjugated synthetic peptide derived from human IGF2R:2201-2400/2491
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=5ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Mouse,Human (predicted: Rabbit,Horse,Cow,Pig,Dog,Chicken,Rat)
For research use only. Not intended for diagnostic or therapeutic use.