Host: Rabbit
Target Protein: RAB7A
IR: Immunogen Range:101-207/207
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 7879
Swiss Prot: P51149
Source: KLH conjugated synthetic peptide derived from human RAB7A:101-207/207
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Mouse,Human (predicted: Rat)
For research use only. Not intended for diagnostic or therapeutic use.