Host: Rabbit

Target Protein: BCA2

IR: Immunogen Range:161-260/304

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 27246

Swiss Prot: Q9Y4L5

Source: KLH conjugated synthetic peptide derived from human ZNF364/BCA2/RNF115:161-260/304 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.