Host: Rabbit
Target Protein: ERG/KCNH2
IR: Immunogen Range:1001-1159/1159
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3757
Swiss Prot: Q12809
Source:
KLH conjugated synthetic peptide derived from human HERG:1001-1159/1159
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.
Size: 200ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Pig,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.