Host: Rabbit
Target Protein: LEF-1
IR: Immunogen Range:331-399/399
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 51176
Swiss Prot: Q9UJU2
Source: KLH conjugated synthetic peptide derived from human LEF-1:331-399/399
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, Flow-Cyt=1ug/test, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse (predicted: Rat,Chicken,Dog,Pig,Cow,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.