bs-1927R [Primary Antibody]
Rabbit  Anti-PLAUR  Polyclonal Antibody
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Host: Rabbit

Target Protein: PLAUR

IR: Immunogen Range:201-300/335

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5329

Swiss Prot: Q03405

Source: KLH conjugated synthetic peptide derived from human PLAUR:201-300/335 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq].

Size: 100ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Cow,Sheep)

For research use only. Not intended for diagnostic or therapeutic use.

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