Host: Rabbit
Target Protein: Lipoprotein lipase
IR: Immunogen Range:401-475/475
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4023
Swiss Prot: P06858
Source: KLH conjugated synthetic peptide derived from human LPL:401-475/475
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=0.2μg /test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: GuineaPig,Sheep,Rabbit,Cow,Pig)
For research use only. Not intended for diagnostic or therapeutic use.