Host: Rabbit

Target Protein: WDFY3

IR: Immunogen Range:951-1050/3526

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23001

Swiss Prot: Q8IZQ1

Source: KLH conjugated synthetic peptide derived from human WDFY3:951-1050/3526 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.