Host: Rabbit

Target Protein: RGS4

IR: Immunogen Range:51-150/205

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5999

Swiss Prot: P49798

Source: KLH conjugated synthetic peptide derived from human RGS4:51-150/205 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.