Host: Rabbit
Target Protein: 5-HTR3
IR: Immunogen Range:301-400/484
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3359
Swiss Prot: P46098
Source: KLH conjugated synthetic peptide derived from human 5-HTR3:301-400/484
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-200, IHC-F=1:100-200, IF=1:50-100
Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Cow)
For research use only. Not intended for diagnostic or therapeutic use.