Host: Rabbit
Target Protein: Prostaglandin I2 Receptor
IR: Immunogen Range:101-200/386
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5739
Swiss Prot: P43119
Source:
KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor:101-200/386
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2?, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main pro-stanoid synthesized by vascular tissues.Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromosome 19. It is expressed as a glycosylated and phosphorylated protein, which is abundantly expressed in vascular tissues such as aorta, lung, atrium and ventricle, as well as in kidney, thymus, spleen and neurons.
Size: 100ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.