Host: Rabbit
Target Protein: MC4R
IR: Immunogen Range:1-50/332
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 4160
Swiss Prot: P32245
Source:
KLH conjugated synthetic peptide derived from human MC4 Receptor:1-50/332
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human
For research use only. Not intended for diagnostic or therapeutic use.