Host: Rabbit

Target Protein: UNC5B

IR: Immunogen Range:188-260/945

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 219699

Swiss Prot: Q8IZJ1

Source: KLH conjugated synthetic peptide derived from human UNC5B:188-260/945 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]