Host: Rabbit

Target Protein: Zic1

IR: Immunogen Range:201-286/447

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7545

Swiss Prot: Q15915

Source: KLH conjugated synthetic peptide derived from human Zic1:201-286/447 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Zic1 is a C2H2 zinc finger transcription factor that controls the expansion of neuronal precursors by inhibiting the progression of neuronal differentiation. Zic1 determines the cerebellar folial pattern by influencing proliferation in the external germinal layer (EGL). Zic1 can bind and transactivate the apolipoprotein E gene.This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3.