Host: Rabbit

Target Protein: BLMH

IR: Immunogen Range:308-400/455

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 642

Swiss Prot: Q13867

Source: KLH conjugated synthetic peptide derived from human BLMH:308-400/455 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].