Host: Rabbit

Target Protein: IRAK4

IR: Immunogen Range:21-120/460

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 51135

Swiss Prot: Q9NWZ3

Source: KLH conjugated synthetic peptide derived from human IRAK4:21-120/460 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]