Host: Rabbit
Target Protein: TMEM106B
IR: Immunogen Range:101-200/274
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 54664
Swiss Prot: Q9NUM4
Source: KLH conjugated synthetic peptide derived from human TMEM106B:101-200/274
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: TMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Sheep,Rabbit,Horse,Cow,Pig,Dog,Rat,Mouse)
For research use only. Not intended for diagnostic or therapeutic use.