Host: Rabbit

Target Protein: SPR

IR: Immunogen Range:101-200/261

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6697

Swiss Prot: P35270

Source: KLH conjugated synthetic peptide derived from human Sepiapterin reductase:101-200/261 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]