Host: Rabbit

Target Protein: 14-3-3 beta

IR: Immunogen Range:51-150/246

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7529

Swiss Prot: P31946

Source: KLH conjugated synthetic peptide derived from human 14-3-3 beta:51-150/246 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: 14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family.
This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.