Host: Rabbit
Target Protein: Mst2
IR: Immunogen Range:351-450/491
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6788
Swiss Prot: Q13188
Source: KLH conjugated synthetic peptide derived from human Mst2:351-450/491
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: MST1/STK4 encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:50, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: Rabbit,Horse,Cow,Pig,Dog)
For research use only. Not intended for diagnostic or therapeutic use.