Host: Rabbit

Target Protein: BTN2A1 + BTN2A2

IR: Immunogen Range:21-120/527

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 11120

Swiss Prot: Q7KYR7

Source: KLH conjugated synthetic peptide derived from human BTN2A1 + BTN2A2:21-120/527 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Butyrophilin is a glycoprotein that is specifically expressed on the apical surface of mammary epithelial cells during lactation and becomes incorporated as an integral protein into the membrane of the milk fat globule during the budding and secretion of fat droplets into milk. BTN2A1 (butyrophilin subfamily 2 member A1), also known as BTF1, is a 527 amino acid single-pass type I membrane B box protein that plays a role in fatty-acid, sterol and lipid metabolism. A member of the immunoglobulin superfamily and BTN/MOG family, BTN2A1 exists as three alternatively spliced isoforms found at high levels in brain, muscle, spleen, pancreas, bone marrow and small intestine. BTN2A1 is expressed at moderate levels in kidney, liver and lung, and is encoded by a gene that maps to human chromosome 6p22.1.