Host: Rabbit

Target Protein: DKK1

IR: Immunogen Range:201-266/266

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22943

Swiss Prot: O94907

Source: KLH conjugated synthetic peptide derived from human DKK1:201-266/266 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]