Host: Rabbit

Target Protein: FIZ1

IR: Immunogen Range:21-120/496

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 84922

Swiss Prot: Q96SL8

Source: KLH conjugated synthetic peptide derived from human FIZ1/ZNF798:21-120/496 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. FIZ1 (FLT3-interacting zinc finger 1), also known as ZNF798 (zinc finger protein 798), is a 496 amino acid zinc-finger protein that contains eleven C2H2-type zinc fingers. Localized to both the cytoplasm and the nucleus and expressed in a wide variety of tissues, FIZ1 is thought to repress the function of Nrl (neural retina leucine zipper) in photoreceptors, possibly regulating the expression of rod-specific genes. Additionally, FIZ1 interacts with the receptor-related tyrosine kinase Flt-3/Flk-2 and, via this interaction, may be involved in the regulation of lymphoid and hematopoietc cells.