Host: Rabbit

Target Protein: FOXRED2

IR: Immunogen Range:21-120/684

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 80020

Swiss Prot: Q8IWF2

Source: KLH conjugated synthetic peptide derived from human FOXRED2:21-120/684 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: FOXRED2 is a 684 amino acid protein that exists as multiple alternatively spliced isoforms. The gene encoding FOXRED2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.