Host: Rabbit
Target Protein: FREM1
IR: Immunogen Range:1201-1300/2179
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 158326
Swiss Prot: Q5H8C1
Source: KLH conjugated synthetic peptide derived from human FREM1:1201-1300/2179
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: FREM1 is a 2,179 amino acid protein that contains one C-type lectin domain, one Calx-beta domain and twelve CSPG repeats. Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Size: 50ul
Concentration: 1mg/ml
Applications: ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Horse)
For research use only. Not intended for diagnostic or therapeutic use.