Host: Rabbit

Target Protein: CYB5D1

IR: Immunogen Range:42-150/228

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 124637

Swiss Prot: Q6P9G0

Source: KLH conjugated synthetic peptide derived from human CYB5D1:42-150/228 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Cytochrome b5 is a membrane-bound heme protein that possesses two heme groups and functions as an electron carrier for many membrane-bound oxygenases. Two isoforms of cytochrome b5, a microsomal membrane-bound form and a cytoplasmic form, are produced by alternative splicing. Mutations in the gene encoding cytochrome b5 are associated with Leber’s hereditary optic neuropathy and myopathy. CYB5D1 (cytochrome b5 domain containing 1) is a 228 amino acid protein that exists as two alternatively spliced variants and contains one cytochrome b5 heme-binding domain, suggesting a similar function to cytochrome b5. The gene encoding CYB5D1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.