Host: Rabbit

Target Protein: phospho-DLC1 (Ser567)

IR: Immunogen Range:PG(p-S)PD

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10395

Swiss Prot: Q96QB1

Source: KLH conjugated Synthesised phosphopeptide derived from human DLC1 around the phosphorylation site of Ser567:PG(p-S)PD 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]