Host: Rabbit

Target Protein: DTX4

IR: Immunogen Range:501-600/619

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23220

Swiss Prot: Q9Y2E6

Source: KLH conjugated synthetic peptide derived from human DTX4:501-600/619 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.