Host: Rabbit

Target Protein: EBP2

IR: Immunogen Range:201-300/306

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10969

Swiss Prot: Q99848

Source: KLH conjugated synthetic peptide derived from human EBP2 :201-300/306 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The replication and stable maintenance of latent Epstein-Barr virus DNA episomes in human cells requires only one viral protein, Epstein-Barr nuclear antigen 1 (EBNA1). EBNA1 binding protein 2, also designated p40/EBP2, is a nuclear protein required for the processing of the 27S pre-rRNA. EBP2 is highly conserved across species and is ubiquitously expressed in human tissues, especially myelogenous leukemia K-562. EBP2 specifically interacts with EBNA1, supporting the long-term maintenance of Epstein-Barr virus plasmids in human cells. The EBNA1-EBP2 complex is important for the stable segregation of Epstein-Barr virus episomes during cell division.