Host: Rabbit

Target Protein: phospho-eIF2B epsilon (Ser539)

IR: Immunogen Range:PD(p-S)R

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8893

Swiss Prot: Q13144

Source: KLH conjugated Synthesised phosphopeptide derived from human EFHC1 around the phosphorylation site of Ser539:PD(p-S)R 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]