Host: Rabbit

Target Protein: B4GALNT1/GM2 synthase

IR: Immunogen Range:451-533/533

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2583

Swiss Prot: Q00973

Source: KLH conjugated synthetic peptide derived from human B4GALNT1/GM2 synthase:451-533/533 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]