Host: Rabbit

Target Protein: ETAA1/ETAA16

IR: Immunogen Range:601-700/926

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 54465

Swiss Prot: Q9NY74

Source: KLH conjugated synthetic peptide derived from human ETAA1/ETAA16:601-700/926 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: ETAA16 (Ewing's tumor-associated antigen 16), also known as ETAA1, is a 926 amino acid cytoplasmic protein that is highly expressed in kidney, brain, liver and Ewing tumor cell lines. ETAA16 undergoes post-translational phosphorylation following DNA damage, most likely by either ATM or ATR, and is suggested to function as a tumour-specific cell surface antigen in Ewing's family of tumour cell lines. The gene encoding ETAA16 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.