Host: Rabbit

Target Protein: Galantide

IR: Immunogen Range:1-20/20

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: N/A

Swiss Prot: N/A

Source: KLH conjugated synthetic peptide of Galantide:1-20/20 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The galanin antagonist Galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C terminal fragment of bradykinin, has been found to improve social memory in `social recognition' tests when i.c.v. administered at doses varying from 6-6000 nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose induced insulin secretion.